A CRISPR View of Cleavage
نویسندگان
چکیده
Seminal studies showed that CRISPR-Cas systems provide adaptive immunity in prokaryotes and promising gene-editing tools from bacteria to humans. Yet, reports diverged on whether some CRISPR systems naturally target DNA or RNA. Here, Samai and colleagues unify the studies, showing that a single type III CRISPR-Cas system cleaves both DNA and RNA targets, independently.
منابع مشابه
Co-transcriptional DNA and RNA Cleavage during Type III CRISPR-Cas Immunity
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ورودعنوان ژورنال:
- Cell
دوره 161 شماره
صفحات -
تاریخ انتشار 2015